Abstract
The expression of cyclin T1 in an autoptic case of AIDS-related cachexia was investigated by immunohistochemistry. When contrasted with normal human tissues, a very similar pattern of expression was found. However, a peculiar distribution of cyclin T1 was noticed in the brown fat and in lymph nodes affected by AIDS-associated lymphadenopathy.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acquired Immunodeficiency Syndrome / complications
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Acquired Immunodeficiency Syndrome / metabolism*
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Acquired Immunodeficiency Syndrome / pathology
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Adipose Tissue, Brown / metabolism
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Adipose Tissue, Brown / pathology
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Adult
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Cachexia / etiology
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Cachexia / metabolism*
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Cachexia / pathology
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Cell Cycle
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Cyclin T
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Cyclins / biosynthesis*
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Germinal Center / metabolism
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Germinal Center / pathology
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Humans
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Immunoenzyme Techniques
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Kidney / metabolism
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Kidney / pathology
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Lymph Nodes / metabolism
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Lymph Nodes / pathology
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Male
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Organ Specificity
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Thymus Gland / metabolism
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Thymus Gland / pathology
Substances
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CCNT1 protein, human
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Cyclin T
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Cyclins