The acrylic content of dental composites poses a risk of adverse reactions. Although the quantities of the substances released are probably too small to cause systemic reactions, local skin or mucosal reactions may arise from direct contact with dental composites. In fact, epidemiological data suggest that most known side effects of dental resins are occupational dermatoses. They may either be due to irritation or allergy. In the Scandinavian countries, occupational dermatoses are relatively common among dental staff, sometimes entailing occupational disability and re-schooling. Most of these reactions can be avoided by observing precautions such as the minimization of the oxygen-inhibited-layer (OIL) in set composites and by using the resin-paste enamel bonding technique. The risk of occupational dermatoses could be reduced by the development of new bonding techniques and careful risk-benefit assessments in the use of dental composites.