Dimeric aporphine alkaloids of Phoenicanthus obliqua from Sri Lanka

J Nat Prod. 2001 Nov;64(11):1465-7. doi: 10.1021/np0102399.

Abstract

A new dimeric aporphine alkaloid, phoenicanthusine (1), and six known alkaloids were isolated from the stem bark of Phoenicanthus obliqua. The structure of 1 was elucidated by 1D ((1)H, (13)C) and 2D ((1)H-(1)H COSY, HMQC, HMBC, and NOESY) NMR and HRMS studies. Phoenicanthusine represents the first example of a N-6--C-4' and C-7--C-5' linked dimeric aporphine alkaloid.

MeSH terms

  • Annonaceae / chemistry*
  • Aporphines / chemistry
  • Aporphines / isolation & purification*
  • Chromatography, Thin Layer
  • Molecular Conformation
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Stems / chemistry
  • Plants, Medicinal / chemistry*
  • Spectrophotometry, Infrared
  • Spectrophotometry, Ultraviolet
  • Sri Lanka

Substances

  • 7,7'-bis(dehydro-O-methylisopiline)
  • 7-dehydronuciferyl-7'-dehydro-O-methylisopiline
  • Aporphines
  • phoenicanthusine
  • urabaine