Abstract
Two new sesquiterpene lactones: 8alpha-(4'-acetoxymethacryloyloxy)-3alpha,9beta-dihydroxy-1(10)E,4Z,11(13)-germacratrien-12,6alpha-olide (1) and 8alpha-(2'E)-(2'-acetoxymethyl-2'-butenoyloxy)-3alpha,9beta-dihydroxy-1(10)E,4Z,11(13)-germacratrien-12,6alphaolide (2), together with the known zoapatanolide A were isolated from the aerial parts of Montanoa tomentosa Cerv. in La Llave et Lex ssp. microcephala (Sch. Bip. In K. Koch) V.A. Funk (Asteraceae). The structures of all compounds were established on the basis of 1D, 2D NMR, and EIMS analysis.
MeSH terms
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Abortifacient Agents, Nonsteroidal / chemistry
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Abortifacient Agents, Nonsteroidal / isolation & purification
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Asteraceae / chemistry*
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Female
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Humans
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Lactones / chemistry
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Lactones / isolation & purification*
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Magnetic Resonance Spectroscopy
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Medicine, Traditional
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Mexico
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Molecular Structure
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Montanoa
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Oxepins / chemistry
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Oxepins / isolation & purification*
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Sesquiterpenes / chemistry
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Sesquiterpenes / isolation & purification*
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Sesquiterpenes, Germacrane*
Substances
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8alpha-(2'E)-(2'-acetoxymethyl-2'-butenoyloxy)-3alpha,9beta-dihydroxy-1(10)E,4Z,11(13)-germacratrien-12,6alphaolide
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8alpha-(4'-acetoxymethacryloyloxy)-3alpha,9beta-dihydroxy-1(10)E,4Z,11(13)-germacratrien-12,6alpha-olide
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Abortifacient Agents, Nonsteroidal
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Lactones
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Oxepins
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Sesquiterpenes
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Sesquiterpenes, Germacrane