Acarbose treatment of postprandial hypoglycemia in children after Nissen fundoplication

J Pediatr. 2001 Dec;139(6):877-9. doi: 10.1067/mpd.2001.119169.

Abstract

Dumping syndrome and postprandial hypoglycemia have been reported after Nissen fundoplication. The physiopathologic mechanisms are poorly understood and a variety of therapies have failed to control the hypoglycemia in these patients. We report a series of 6 infants with postprandial hypoglycemia after Nissen fundoplication who were treated successfully with acarbose.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Acarbose / therapeutic use*
  • Child, Preschool
  • Female
  • Fundoplication / adverse effects*
  • Gastroesophageal Reflux / surgery*
  • Humans
  • Hypoglycemia / drug therapy*
  • Hypoglycemia / etiology*
  • Hypoglycemic Agents / therapeutic use*
  • Infant
  • Male
  • Postprandial Period / drug effects*

Substances

  • Hypoglycemic Agents
  • Acarbose