Impaired set-shifting ability and therapeutic response in obsessive-compulsive disorder

J Neuropsychiatry Clin Neurosci. 2001 Fall;13(4):508-10. doi: 10.1176/jnp.13.4.508.

Abstract

Set-shifting ability and therapeutic response to serotonin reuptake inhibitors were investigated in 20 patients with obsessive-compulsive disorder. A clear relationship was found between impaired performance on two Wisconsin Card Sorting subtests (categories completed and perseverative errors) and positive treatment response.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Attention / drug effects*
  • Discrimination Learning / drug effects*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests*
  • Obsessive-Compulsive Disorder / diagnosis
  • Obsessive-Compulsive Disorder / drug therapy*
  • Obsessive-Compulsive Disorder / psychology
  • Selective Serotonin Reuptake Inhibitors / therapeutic use*
  • Set, Psychology*
  • Treatment Outcome

Substances

  • Serotonin Uptake Inhibitors