Pharmacodynamic monitoring of lymphocyte proliferation and TGF-beta 1 expression at cyclosporine a (CyA) trough levels (C(0)) and 2 hours after intake (C(2)) of CyA in human renal allograft recipients

Transplant Proc. 2001 Nov-Dec;33(7-8):3148-50. doi: 10.1016/s0041-1345(01)02341-7.
No abstract available

MeSH terms

  • Antigens, CD / immunology
  • CD3 Complex / immunology
  • Cyclosporine / blood
  • Cyclosporine / pharmacology
  • Cyclosporine / therapeutic use*
  • Drug Monitoring / methods
  • Humans
  • Immunosuppressive Agents / blood
  • Immunosuppressive Agents / pharmacology
  • Immunosuppressive Agents / therapeutic use
  • Kidney Transplantation / immunology*
  • Kidney Transplantation / physiology
  • Lymphocyte Activation / drug effects*
  • Lymphocytes / drug effects
  • Lymphocytes / immunology
  • Metabolic Clearance Rate
  • Transforming Growth Factor beta / biosynthesis
  • Transforming Growth Factor beta / blood
  • Transplantation, Homologous

Substances

  • Antigens, CD
  • CD3 Complex
  • Immunosuppressive Agents
  • Transforming Growth Factor beta
  • Cyclosporine