CD4 and CD8 cytokine-producing T cells are transiently reduced following cyclosporine intake: maximal inhibition occurs at 2 hours coincidental with drug C(max)

Transplant Proc. 2001 Nov-Dec;33(7-8):3310-2. doi: 10.1016/s0041-1345(01)02406-x.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • CD4-Positive T-Lymphocytes / drug effects
  • CD4-Positive T-Lymphocytes / immunology*
  • CD8-Positive T-Lymphocytes / drug effects
  • CD8-Positive T-Lymphocytes / immunology*
  • Cyclosporine / pharmacology*
  • Cytokines / biosynthesis*
  • Humans
  • Immunosuppressive Agents / pharmacology*
  • Interferon-gamma / biosynthesis
  • Interleukin-2 / biosynthesis
  • Kinetics
  • Time Factors
  • Transplantation Immunology*

Substances

  • Cytokines
  • Immunosuppressive Agents
  • Interleukin-2
  • Interferon-gamma
  • Cyclosporine