Systemic steroids for the management of obstructive subglottic hemangioma

J Otolaryngol. 2000 Dec;29(6):361-6.

Abstract

Subglottic hemangioma is a recognized cause of paediatric upper airway obstruction. We present 14 patients with subglottic hemangioma treated between 1984 and 1997,4 of whom had associated extralaryngeal hemangiomatous lesions (28%). The degree of upper airway obstruction ranged between 20% and 90%. Patients with subglottic hemangioma who had obstruction of the laryngeal lumen more than 25% and those with obstructive symptoms were treated with systemic steroids. The patients were followed clinically, radiographically, and with repetitive bronchoscopies. Nine of 10 patients (90%) have responded clinically to systemic steroids. There were no major complications from the systemic steroid treatment. One patient developed a cushingoid face that was reversed after the cessation of steroid therapy. The purpose of this study is to show that systemic steroids, with or without short-term intubation after diagnostic bronchoscopy, can be used as a safe and effective alternative in the management of obstructive paediatric subglottic hemangiomas.

MeSH terms

  • Airway Obstruction / drug therapy*
  • Airway Obstruction / epidemiology
  • Airway Obstruction / etiology
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use*
  • Child, Preschool
  • Dexamethasone / administration & dosage
  • Dexamethasone / therapeutic use*
  • Drug Administration Schedule
  • Female
  • Hemangioma / complications
  • Hemangioma / drug therapy*
  • Humans
  • Infant
  • Laryngeal Neoplasms / complications
  • Laryngeal Neoplasms / drug therapy*
  • Male
  • Prednisolone / administration & dosage
  • Prednisolone / therapeutic use*

Substances

  • Anti-Inflammatory Agents
  • Dexamethasone
  • Prednisolone