Results of the MXM Digisonic auditory brainstem implant clinical trials in Europe

Otol Neurotol. 2002 Jan;23(1):56-60. doi: 10.1097/00129492-200201000-00014.

Abstract

Objective: To assess the potential benefit of the MXM auditory brainstem implant for patients with neurofibromatosis type 2.

Study design: Retrospective case review.

Setting: Tertiary referral centers.

Patients: Fourteen patients with neurofibromatosis type 2 and bilateral acoustic neuromas underwent implantation with the MXM auditory brainstem implant during surgery to remove the second-side tumor.

Results: There were no complications related to the auditory brainstem implantation. Auditory sensations were present for 12 of 14 patients (86%). Global results indicated an improved quality of life for the patients receiving auditory sensations, in part because of their auditory orientation within the environment. Eighty-nine percent of patients tested with an open-set sentence test demonstrated enhancement of speech understanding as a result of lip-reading improvement when auditory brainstem implant sound was combined with lip-reading. A few patients (36%) had some speech understanding in sound-only mode. One patient was able to have limited phone conversations.

Conclusion: These results indicate that significant auditory benefit can be derived from the MXM auditory brainstem implant.

MeSH terms

  • Adolescent
  • Adult
  • Auditory Perception / physiology
  • Clinical Trials as Topic
  • Deafness / etiology
  • Deafness / surgery
  • Evoked Potentials, Auditory, Brain Stem / physiology*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neurofibromatosis 2 / complications
  • Neuroma, Acoustic / complications
  • Otologic Surgical Procedures / methods
  • Postoperative Care
  • Quality of Life
  • Retrospective Studies
  • Treatment Outcome