Objective: To investigate the current situation of clinical trial about preventive research paper on respiratory diseases in China. To stress the design of the research, and to improve the quality of the studies.
Methods: All the preventive and treatment studies of Chinese Journal of Tuberculosis and Respiratory Diseases (1978-1997) were assessed according to evidence based medicine (EBM) standard.
Results: In the past 20 years, 394 preventive study papers were published, 41 were random control trial (RCT), 50 were clinical control trial (CCT), the total percentage of RCT and CCT was 23.1%, and quality problem also existed.
Conclusions: The design of the study in the respiratory diseases is not rigorous, thus the accuracy of the result is greatly affected. Improving the design of the research and the statistics method is very important to improve the quality of the research.