Abstract
An anomalous high frequency of ATL was observed in a remote 'noir maroons' village of French Guiana. Since it is not clear if HTLV-I is responsible for different frequencies of disease in different geographical areas, we undertook a comparison of the population with a similar one located in Gabon. We found a much higher degree of gp46 surface envelope glycoprotein sequence conservation in the Guianese village than in the Gabonese one.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Base Sequence
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Conserved Sequence
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DNA, Viral
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Female
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French Guiana / epidemiology
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Gabon / epidemiology
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Gene Products, env / genetics
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Genetic Variation*
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Human T-lymphotropic virus 1 / genetics*
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Humans
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Leukemia-Lymphoma, Adult T-Cell / epidemiology
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Leukemia-Lymphoma, Adult T-Cell / virology*
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Male
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Molecular Sequence Data
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Phylogeny
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Retroviridae Proteins, Oncogenic / genetics
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Sequence Alignment
Substances
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DNA, Viral
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Gene Products, env
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Retroviridae Proteins, Oncogenic
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gp46 protein, Human T-cell leukemia virus type I