Effects of acidum vitamin A on tyrosinase activity

Chin Med J (Engl). 2001 Apr;114(4):415-7.

Abstract

Objective: To investigate the effect of acidum vitamin A on tyrosinase activity and provide experimental evidence for therapy of pigment disorder of skin.

Methods: Tyrosinase activity was estimated by measuring the rate of oxidation of DL-dopa.

Results: The levels of tyrosinase activity in the acidum vitamin A group were significantly greater than those of the control group (P < 0.01).

Conclusion: Tyrosinase activity can be increasingly induced by acidum vitamin A.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Monophenol Monooxygenase / genetics
  • Monophenol Monooxygenase / metabolism*
  • Pigmentation / drug effects
  • Receptors, Retinoic Acid / drug effects
  • Receptors, Retinoic Acid / physiology
  • Tretinoin / pharmacology*

Substances

  • Receptors, Retinoic Acid
  • Tretinoin
  • Monophenol Monooxygenase