Apoptosis-inducing cleavage of caspases by trimidox, an inhibitor of ribonucleotide reductase

Adv Exp Med Biol. 2000:486:125-30. doi: 10.1007/0-306-46843-3_25.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apoptosis*
  • Benzamidines / pharmacology*
  • Caspase 3
  • Caspase Inhibitors*
  • DNA Fragmentation
  • Enzyme Inhibitors / pharmacology*
  • Gene Expression / drug effects
  • HL-60 Cells
  • Humans
  • Poly(ADP-ribose) Polymerases / metabolism
  • Proto-Oncogene Proteins c-myc / genetics
  • Ribonucleotide Reductases / antagonists & inhibitors*

Substances

  • 3,4,5-trihydroxybenzamidoxime
  • Benzamidines
  • Caspase Inhibitors
  • Enzyme Inhibitors
  • Proto-Oncogene Proteins c-myc
  • Ribonucleotide Reductases
  • Poly(ADP-ribose) Polymerases
  • CASP3 protein, human
  • Caspase 3