Objective: To evaluate the effect of combined use of Chinese herbal medicine, Captopril and Metoprolol in treating mild-middle degree congestive heart failure.
Methods: One hundred and fifty patients studied were divided into 3 groups, the Group A treated with Chinese herbal medicine, Group B treated with Captopril plus Metoprolol and Group C treated with both Chinese and western medicines. Parameters on cardiac functions were observed and compared 3 weaks and 3 months after treatment respectively.
Results: (1) The cure rate in the Group A, B and C was 72%, 86% and 94% respectively. (2) Effect of echocardiogram: ultrasound cardiogram showed that the left ventricular diastolic diameter in Group C was less significantly than that in Group A and B (P < 0.05). (3) The eject fraction in Group C was higher than that in the other two groups (P < 0.05). (4) The 24 hours dynamic electrocardiogram demonstrated a significant lowering occurrence of ventricular premature contraction in Group C in comparing with that in Group A and B (P < 0.05).
Conclusion: Good effect would be expected in treating mild-middle degree congestive heart failure by using Chinese herbal medicine combined with Captopril and Metoprolol.