Abstract
The structure of ostreocin D, a palytoxin analog isolated from the marine dinoflagellate Ostreopsis siamensis, was found to be 42-hydroxy-3,26-didemethyl-19,44-dideoxypalytoxin by detailed 2D NMR analyses of intact ostreocin D and its ozonolysis products. Partial stereochemical assignments were done. This result indicates that the dinoflagellate O. siamensis is one of the biogenetic origins of palytoxin.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acrylamides / chemistry
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Acrylamides / isolation & purification*
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Animals
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Bridged Bicyclo Compounds, Heterocyclic / chemistry
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Bridged Bicyclo Compounds, Heterocyclic / isolation & purification*
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Cnidarian Venoms
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Dinoflagellida / chemistry*
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Magnetic Resonance Spectroscopy
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Marine Toxins / chemistry
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Marine Toxins / isolation & purification*
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Molecular Structure
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Pyrans / chemistry
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Pyrans / isolation & purification*
Substances
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Acrylamides
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Bridged Bicyclo Compounds, Heterocyclic
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Cnidarian Venoms
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Marine Toxins
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Pyrans
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palytoxin
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ostreocin D