Abstract
Autonomic dysfunction occurs in the adult population with irritable bowel syndrome, but this association is not recognized in children. A mother and son with functional abdominal pain unresponsive to conventional treatment had complete resolution of symptoms with treatment directed at the autonomic dysfunction identified by testing. The authors recommend autonomic testing in patients with functional abdominal pain and suggest that autonomic dysfunction plays a direct and intrinsic role in the mechanism of these disorders and their symptoms.
MeSH terms
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Adrenergic beta-Antagonists / adverse effects
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Adrenergic beta-Antagonists / therapeutic use
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Adult
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Atenolol / therapeutic use
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Autonomic Nervous System Diseases / complications
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Autonomic Nervous System Diseases / drug therapy
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Autonomic Nervous System Diseases / genetics*
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Child
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Fatigue / chemically induced
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Female
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Gastrointestinal Diseases / complications
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Gastrointestinal Diseases / drug therapy
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Gastrointestinal Diseases / genetics*
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Humans
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Hypnotics and Sedatives / therapeutic use
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Male
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Phenobarbital / therapeutic use
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Propranolol / adverse effects
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Propranolol / therapeutic use
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Retreatment
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Sleep Initiation and Maintenance Disorders / chemically induced
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Sleep Initiation and Maintenance Disorders / drug therapy
Substances
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Adrenergic beta-Antagonists
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Hypnotics and Sedatives
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Atenolol
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Propranolol
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Phenobarbital