Abstract
Fractionation of the acetone extract of Junceella juncea collected in Taiwan resulted in the isolation of a new briarane, designated juncenolide A (1). The structure of 1 was determined on the basis of 2D NMR techniques, including COSY, HSQC, HMBC, and NOESY experiments, and was also confirmed by X-ray crystallographic analysis.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cnidaria / chemistry*
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Colonic Neoplasms
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Crystallography, X-Ray
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Diterpenes / chemistry
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Diterpenes / isolation & purification*
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Diterpenes / pharmacology
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Drug Screening Assays, Antitumor
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Humans
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Inhibitory Concentration 50
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KB Cells
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Mass Spectrometry
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Molecular Conformation
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Spectrophotometry, Infrared
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Taiwan
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Tumor Cells, Cultured / drug effects