Selectivity in an encapsulated cycloaddition reaction

Jian Chen; Julius Rebek Jr

doi:10.1021/ol0168115

Selectivity in an encapsulated cycloaddition reaction

Org Lett. 2002 Feb 7;4(3):327-9. doi: 10.1021/ol0168115.

Authors

Jian Chen¹, Julius Rebek Jr

Affiliation

¹ The Skaggs Institute for Chemical Biology, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

PMID: 11820871
DOI: 10.1021/ol0168115

Abstract

A 1,3-dipolar cycloaddition takes place within a reversibly formed, self-assembled capsule. The reaction proceeds through an unsymmetrically loaded encapsulation complex with absolute regioselectivity.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Chemical Phenomena
Chemistry, Inorganic*
Magnetic Resonance Spectroscopy
Molecular Structure