Acute abdomen during adjuvant chemotherapy: superior mesenteric artery thrombosis associated with CMF chemotherapy

Clin Oncol (R Coll Radiol). 2001;13(6):441-3. doi: 10.1053/clon.2001.9309.

Abstract

We report a case of superior mesenteric artery thrombosis in a 57-year-old woman undergoing chemotherapy for T1N1M0, breast cancer. Although cancer itself is associated with an increased risk of thrombotic events, treatment with chemotherapy and/or tamoxifen in breast cancer patients increases this risk. Most cases reported are of venous thromboembolism; arterial events are rare.

Publication types

  • Case Reports

MeSH terms

  • Abdomen, Acute / chemically induced*
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Breast Neoplasms / drug therapy
  • Chemotherapy, Adjuvant
  • Cyclophosphamide / adverse effects*
  • Female
  • Fluorouracil / adverse effects*
  • Humans
  • Mesenteric Artery, Superior / drug effects
  • Mesenteric Vascular Occlusion / chemically induced*
  • Methotrexate / adverse effects*
  • Middle Aged
  • Thrombosis / chemically induced*

Substances

  • Cyclophosphamide
  • Fluorouracil
  • Methotrexate

Supplementary concepts

  • CMF regimen