Role of T cells in abscess formation

Curr Opin Microbiol. 2002 Feb;5(1):92-6. doi: 10.1016/s1369-5274(02)00292-8.

Abstract

A series of recent studies have shed new light on the strategy used by certain bacterial pathogens to induce a classic infectious process: abscess formation. This work describes how zwitterionic polysaccharides on the surface of these organisms interact with the host immune system in general, and with T cells in particular, to coordinate this pathobiologic response.

Publication types

  • Review

MeSH terms

  • Abscess / etiology*
  • Abscess / microbiology
  • Abscess / prevention & control*
  • Animals
  • Anions / chemistry*
  • Bacteroides fragilis / chemistry*
  • Bacteroides fragilis / metabolism*
  • CD4-Positive T-Lymphocytes / immunology*
  • Cations / chemistry*
  • Cell Communication / immunology*
  • Models, Biological
  • Polysaccharides, Bacterial / chemistry*
  • Polysaccharides, Bacterial / metabolism*
  • Rats
  • T-Lymphocytes / chemistry
  • T-Lymphocytes / immunology*

Substances

  • Anions
  • Cations
  • Polysaccharides, Bacterial