In the common opinion amongst woman, the surgical removal of the uterus and ovaries can be a cause of limited physical and sexual activity and have an effect on their attractiveness. The majority of women after hysterectomy can be permanently depressed and can also show symptoms of mixed anxiety-depressive disorder. The review of literature allows for an assumption that the topic of anxiety and depression should not be underrated, by treating it as an exaggerated theme, as some researchers do. By considering the research quoted in this paper the collected directions of diagnostic and therapeutic procedures undertaken by the psychiatrist and psychologist can be used before the planned operation. Special consideration must be given to patients who have a history of affective disorders or sexual abuse. Pharmacotherapy and psychotherapy should applied in order to prevent post-operative affective disorders.