Abstract
A growing body of evidence indicates that vascular growth factors and their receptors are activated after stroke, and these factors may contribute to ischemic cell damage and to angiogenesis during recovery from stroke. In this review, we focus on recent evidence for roles of vascular endothelial growth factor (VEGF) and angiopoietin 1 (Ang 1) in blood-brain barrier (BBB) leakage and angiogenesis after focal cerebral ischemia.
Publication types
-
Research Support, U.S. Gov't, P.H.S.
-
Review
MeSH terms
-
Angiopoietin-1
-
Animals
-
Blood-Brain Barrier / drug effects
-
Blood-Brain Barrier / physiology*
-
Brain Ischemia / physiopathology*
-
Endothelial Growth Factors / pharmacology
-
Endothelial Growth Factors / physiology*
-
Humans
-
Lymphokines / pharmacology
-
Lymphokines / physiology*
-
Membrane Glycoproteins / physiology*
-
Mice
-
Neovascularization, Physiologic*
-
Rats
-
Vascular Endothelial Growth Factor A
-
Vascular Endothelial Growth Factors
Substances
-
Angiopoietin-1
-
Angpt1 protein, mouse
-
Angpt1 protein, rat
-
Endothelial Growth Factors
-
Lymphokines
-
Membrane Glycoproteins
-
Vascular Endothelial Growth Factor A
-
Vascular Endothelial Growth Factors