Abstract
Five new coumaronochromones, euchretins J-N (1 - 5), along with twelve known compounds, euchretins A (6), C, D, F, H, I, (+)-matrine, (-)-cytisine, quercetin, trifolirhizin, retusin 8-methyl ether, and genistein, were isolated from the methanolic extracts of Euchresta formosana. The structures of compounds 1 - 5 were established by spectroscopic analyses. Among them, compounds 1, 4 and 6 were demonstrated to have cytotoxicity against 59T cell line, and compound 1 was also found to be active against SCM-1 cell line.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Chromones / chemistry
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Chromones / isolation & purification
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Chromones / pharmacology*
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Coumarins / chemistry
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Coumarins / isolation & purification
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Coumarins / pharmacology*
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Fabaceae*
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Flavonoids / chemistry
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Flavonoids / isolation & purification
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Flavonoids / pharmacology
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Humans
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Magnetic Resonance Spectroscopy
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Medicine, Chinese Traditional
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Molecular Structure
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Plant Extracts / chemistry
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacology*
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Plant Roots / chemistry*
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Tumor Cells, Cultured / drug effects
Substances
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Chromones
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Coumarins
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Flavonoids
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Plant Extracts