Abstract
A new 14-step synthesis of (+)-oxybiotin, an oxygen analogue of (+)-biotin, was achieved starting from D-xylose by use of selected 2,5-anhydro sugar derivatives as key intermediates.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Biotin / analogs & derivatives
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Biotin / chemical synthesis*
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Biotin / chemistry
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Molecular Conformation
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Xylose / chemistry*