[The correlation of free radicals induced by cadmium toxicess with erythrocyte injury and band3 expression]

Zhonghua Yu Fang Yi Xue Za Zhi. 1999 Jan;33(1):18-20.
[Article in Chinese]

Abstract

Objective: To study the correlation of hydrogen peroxide induced by cadmium ion with erythrocyte injury and band3 expression.

Methods: It was application immunoscanning electronmicroscopy and cytochemistry and EDX methods.

Result: Cadmium ion not only induced a lot of hydrogen peroxide but also caused serious distortion of erythrocyte.

Conclusion: Cadmium ion-induced free radicals lead to oxygen free radical damage of membrane and crytoskelecton of erythrocyte, affecting the stability and deformability and band3 expression in erythrocyte.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Anion Exchange Protein 1, Erythrocyte / analysis*
  • Cadmium / toxicity*
  • Erythrocytes / drug effects*
  • Erythrocytes / metabolism
  • Free Radicals
  • Hydrogen Peroxide / metabolism
  • Rats
  • Rats, Wistar

Substances

  • Anion Exchange Protein 1, Erythrocyte
  • Free Radicals
  • Cadmium
  • Hydrogen Peroxide