Wnt signalling: a moving picture emerges from van gogh

Curr Biol. 2002 Feb 19;12(4):R126-8. doi: 10.1016/s0960-9822(02)00704-2.

Abstract

Recent studies on vertebrate homologues of the van gogh/strabismus (vang/stbm) gene, a key player in planar cell polarity signalling in Drosophila, show that vang/stbm is involved in patterning and morphogenesis during vertebrate gastrulation where it modulates two distinct Wnt signals.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Polarity
  • Drosophila / cytology
  • Drosophila / embryology*
  • Drosophila / metabolism*
  • Drosophila Proteins*
  • Epithelial Cells / cytology
  • Epithelial Cells / metabolism
  • Gastrula / cytology
  • Gastrula / metabolism
  • Membrane Proteins / metabolism*
  • Morphogenesis
  • Proto-Oncogene Proteins / metabolism*
  • Signal Transduction*
  • Wnt Proteins
  • Zebrafish Proteins*

Substances

  • Drosophila Proteins
  • Membrane Proteins
  • Proto-Oncogene Proteins
  • Vang protein, Drosophila
  • Wnt Proteins
  • Zebrafish Proteins