ER dislocation: Cdc48p/p97 gets into the AAAct

Curr Biol. 2002 Mar 5;12(5):R182-4. doi: 10.1016/s0960-9822(02)00738-8.

Abstract

Misfolded or unassembled proteins present in the lumen of the endoplasmic reticulum are exported to the cytosol and degraded. Recent studies have implicated a complex containing the AAA ATPase Cdc48p/p97 in the export process.

Publication types

  • Review

MeSH terms

  • Adenosine Triphosphatases / metabolism
  • Animals
  • Biological Transport, Active
  • Cell Cycle Proteins / metabolism*
  • Endoplasmic Reticulum / metabolism*
  • Humans
  • Models, Biological
  • Protein Folding
  • Proteins / chemistry
  • Proteins / metabolism
  • Valosin Containing Protein

Substances

  • Cell Cycle Proteins
  • Proteins
  • Adenosine Triphosphatases
  • Valosin Containing Protein