[Adenocarcinoma of the cervix--stage IB: results of treatment and prognostic factors]

Ginekol Pol. 2001 Dec;72(12A):1478-84.
[Article in Polish]

Abstract

The study presents the results of treatment of 63 women with stage IB adenocarcinoma of the cervix. The treatment consist of radical Wertheim-Meigs hysterectomy with adjuvant brachytherapy or external beam irradiation. A statistical analysis with Kaplan-Meier and cox model was conducted to assess the influence of selected prognostic factors on survival. After 5-year long follow-up 73.4% of patients were alive without recurrence. The results of univariate analysis showed that metastatic pelvic nodes, cervical tumor size of more than 4 cm and the presence of microscopic parametrial infiltration had a statistically significant negative influence on survival. In a multivariate analysis tumor size of more than 4 cm and microscopic parametrial involvement had an independent negative impact on survival (relative risk of death--12.1 and 15.7).

Publication types

  • English Abstract

MeSH terms

  • Adenocarcinoma / pathology*
  • Adenocarcinoma / therapy*
  • Adult
  • Aged
  • Brachytherapy / methods
  • Female
  • Humans
  • Hysterectomy
  • Middle Aged
  • Multivariate Analysis
  • Neoplasm Recurrence, Local
  • Neoplasm Staging
  • Prognosis
  • Radioimmunotherapy / methods
  • Radiotherapy, Adjuvant
  • Risk Factors
  • Survival Rate
  • Time Factors
  • Uterine Cervical Neoplasms / pathology*
  • Uterine Cervical Neoplasms / therapy*