Apolipoprotein E gender effects on cognitive performance in age-associated memory impairment

J Neuropsychiatry Clin Neurosci. 2002 Winter;14(1):80-3. doi: 10.1176/jnp.14.1.80.

Abstract

Among 100 individuals with age-associated memory impairment (AAMI), APOE E4 carriers performed worse on memory. However, when subjects were considered by gender, this effect was only observed in females. APOE E4 may have a more robust cognitive influence on female than on male individuals with AAMI.

Publication types

  • Clinical Trial
  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aging / physiology*
  • Apolipoproteins E / genetics*
  • Cognition / physiology*
  • Female
  • Genotype
  • Humans
  • Male
  • Memory Disorders / genetics*
  • Memory Disorders / psychology*
  • Neuropsychological Tests
  • Psychiatric Status Rating Scales
  • Psychomotor Performance / physiology
  • Sex Characteristics

Substances

  • Apolipoproteins E