Developments in hydrogenation technology for fine-chemical and pharmaceutical applications

Curr Opin Drug Discov Devel. 2001 Nov;4(6):745-55.

Abstract

The continuous innovation in hydrogenation technology is testimony to its growing importance in the manufacture of specialty and fine chemicals. New developments in equipment, process intensification and catalysis represent major themes that have undergone recent advances. Developments in chiral catalysis, methods to support and fix homogeneous catalysts, novel reactor and mixing technology, high-throughput screening, supercritical processing, spectroscopic and electrochemical online process monitoring, monolithic and structured catalysts, and sonochemical activation methods illustrate the scope and breadth of evolving technology applied to hydrogenation.

Publication types

  • Review

MeSH terms

  • Catalysis
  • Chemistry, Pharmaceutical / methods*
  • Hydrogenation*
  • Pharmaceutical Preparations / chemistry*
  • Ultrasonics

Substances

  • Pharmaceutical Preparations