Levels of thermostable direct hemolysin produced by Vibrio parahaemolyticus O3:K6 and other serovars grown anaerobically with the presence of a bile acid

Ro Osawa; Eiji Arakawa; Tadayuki Okitsu; Shiro Yamai; Haruo Watanabe

doi:10.1007/s00284-001-0051-3

Levels of thermostable direct hemolysin produced by Vibrio parahaemolyticus O3:K6 and other serovars grown anaerobically with the presence of a bile acid

Curr Microbiol. 2002 Apr;44(4):302-5. doi: 10.1007/s00284-001-0051-3.

Authors

Ro Osawa¹, Eiji Arakawa, Tadayuki Okitsu, Shiro Yamai, Haruo Watanabe

Affiliation

¹ Department of Bioscience, Graduate School of Science and Technology, Kobe University, Rokko-dai 1-1-I, Nada-ku, Kobe, 657-8501, Japan.

PMID: 11910503
DOI: 10.1007/s00284-001-0051-3

Abstract

Twenty-three V. parahaemolyticus strains, including 12 pandemic O3:K6 strains, were examined for their growth and production of thermostable direct hemolysin (TDH) under an anaerobic culture condition with or without presence of a bile acid, taurocholic acid (TCA). Both bacterial growth and TDH production were markedly enhanced by TCA for a majority of the strains, but the scale of the TDH production was disproportionately greater than that of the corresponding growth for 14 strains. Such enhancement was, however, not specific to the pandemic strains.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Aerobiosis
Bacterial Toxins / biosynthesis*
Bile Acids and Salts*
Culture Media
Electrophoresis, Gel, Pulsed-Field
Food Microbiology*
Genotype
Hemolysin Proteins / biosynthesis*
Humans
Indonesia
Japan
Korea
Seawater
Taurocholic Acid
Thailand
United States
Vibrio Infections / microbiology
Vibrio parahaemolyticus / drug effects
Vibrio parahaemolyticus / growth & development
Vibrio parahaemolyticus / metabolism*

Substances

Bacterial Toxins
Bile Acids and Salts
Culture Media
Hemolysin Proteins
thermostable direct hemolysin
Taurocholic Acid