Replacement of the intervening amino acid sequence of a Syk-binding diphosphopeptide by a nonpeptide spacer with preservation of high affinity

Chembiochem. 2002 Mar 1;3(2-3):238-42. doi: 10.1002/1439-7633(20020301)3:2/3<238::AID-CBIC238>3.0.CO;2-W.
No abstract available

MeSH terms

  • Amino Acid Sequence
  • Enzyme Precursors / chemistry*
  • Enzyme Precursors / metabolism
  • Enzyme Precursors / physiology
  • Intracellular Signaling Peptides and Proteins
  • Models, Molecular
  • Molecular Sequence Data
  • Phosphopeptides / chemical synthesis*
  • Phosphopeptides / metabolism
  • Phosphopeptides / physiology
  • Protein-Tyrosine Kinases / chemistry*
  • Protein-Tyrosine Kinases / metabolism
  • Protein-Tyrosine Kinases / physiology
  • Recombinant Proteins / chemistry
  • Recombinant Proteins / metabolism
  • Surface Plasmon Resonance
  • Syk Kinase

Substances

  • Enzyme Precursors
  • Intracellular Signaling Peptides and Proteins
  • Phosphopeptides
  • Recombinant Proteins
  • Protein-Tyrosine Kinases
  • Syk Kinase