Randomized clinical trials in rectal and anal cancer

Surg Oncol Clin N Am. 2002 Jan;11(1):149-72, ix. doi: 10.1016/s1055-3207(03)00079-6.

Abstract

Treatment of rectal cancer has changed dramatically over the past two decades. Radical surgery alone for resectable rectal cancer has been replaced by combined modality therapy. Interest in optimizing sphincter preservation and quality of life motivated surgeons to seek less radical surgery without compromising oncologic principles.

Publication types

  • Review

MeSH terms

  • Anus Neoplasms / therapy
  • Carcinoma, Squamous Cell / therapy*
  • Evidence-Based Medicine
  • Humans
  • Medical Oncology
  • Prospective Studies
  • Randomized Controlled Trials as Topic*
  • Rectal Neoplasms / therapy*