Demonstrated use of metered-dose inhalers and peak flow meters by children and adolescents with acute asthma exacerbations

Arch Pediatr Adolesc Med. 2002 Apr;156(4):378-83. doi: 10.1001/archpedi.156.4.378.

Abstract

Objectives: To determine the ability of children and adolescents with acute asthma exacerbations to adhere to national guidelines for proper metered-dose inhaler (MDI) and peak flow meter (PFM) technique and to define characteristics associated with improper use.

Design: A prospective study in which the patients were instructed to use a placebo MDI or a PFM in the emergency department exactly as at home. Technique was graded on the basis of performance of specific steps recommended by national guidelines.

Setting and participants: Children and adolescents (aged 2-18 years) with acute asthma exacerbations in the emergency department of an urban children's hospital with acute asthma.

Results: Thirty-three (45.2%) of 73 patients using an MDI (MDI group) demonstrated multiple steps improperly compared with 60 (44.4%) of 135 using an MDI with a holding chamber (MDI-HC group; P =.92). In the MDI group, young ages of the patients (P<.008) and the parents (P<.003) were associated with improper use. In the MDI-HC group, factors independently and significantly associated with improper use were no hospitalizations within the past year, parent assistance of the patient with MDI-HC use, and nondaily use of the MDI-HC. Also, 165 (82.9%) of 199 children who, per national guidelines, should be using a PFM at home, did not. Eighty-two (73.9%) of 111 patients demonstrated perfect performance of all PFM steps.

Conclusions: Among children with acute asthma, we found high rates of improper MDI use and PFM underuse. A greater emphasis must be placed on teaching methods to optimize drug delivery and to instruct patients about the importance of self-monitoring of disease severity.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Acute Disease
  • Administration, Inhalation
  • Adolescent
  • Anti-Asthmatic Agents / administration & dosage*
  • Asthma / drug therapy*
  • Child
  • Child, Preschool
  • Emergency Service, Hospital
  • Female
  • Hospitals, Pediatric
  • Humans
  • Logistic Models
  • Male
  • Nebulizers and Vaporizers*
  • Odds Ratio
  • Patient Education as Topic
  • Prospective Studies
  • Risk Factors

Substances

  • Anti-Asthmatic Agents