Introduction: Human intestinal spirochetosis has been known since the end of the nineteenth century.
Observation: We report one case of intestinal spirochetosis revealed by chronic diarrhoea and diagnosed on colonic biopsies. The chronic diarrhoea disappeared with antibiotherapy.
Commentaries: The prevalence of intestinal spirochetosis in rectal and colonic biopsies, among patients with digestive disorders, varies in occidental countries from 2% to 7%. Presently, the pathogenic role of intestinal spirochetosis is controversial.