Assembly of fingerprint contigs: parallelized FPC

Bioinformatics. 2002 Mar;18(3):484-5. doi: 10.1093/bioinformatics/18.3.484.

Abstract

Summary: One of the more common uses of the program FingerPrint Contigs (FPC) is to assemble random restriction digest 'fingerprints' of overlapping genomic clones into contigs. To improve the rate of assembling contigs from large fingerprint databases we have adapted FPC so that it can be run in parallel on multiple processors and servers. The current version of 'parallelized FPC' has been used in our laboratory to assemble mammalian BAC fingerprint databases, each containing more than 300000 BAC fingerprints.

Availability: This parallelized version of FPC is available under the GNU GPL licence, and can be downloaded from ftp://ftp.bcgsc.bc.ca/pub/fpcd.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Algorithms*
  • Animals
  • Base Sequence
  • Cloning, Molecular*
  • Computing Methodologies*
  • Contig Mapping / methods*
  • Contig Mapping / statistics & numerical data
  • DNA Fingerprinting / methods
  • Databases, Genetic*
  • Humans
  • Internet
  • Mice
  • Molecular Sequence Data
  • Restriction Mapping
  • Sensitivity and Specificity
  • Sequence Tagged Sites
  • Software
  • Time Factors