Abstract
Good progress has been made in the researches on correlating genes of breast cancer in recent years. Quite a few kinds of genes such as susceptibility gene, oncogene and tumor suppressor genes have been found with implications for diagnosis, therapy and prognosis. Abnormality of breast cancer susceptibility gene (BRCA) is of great significance, especially in the development of breast cancer.
MeSH terms
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BRCA1 Protein / genetics
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BRCA2 Protein / genetics
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Breast Neoplasms / genetics*
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Cyclin-Dependent Kinase Inhibitor p16 / genetics
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Cyclin-Dependent Kinase Inhibitor p21
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Cyclins / genetics
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Female
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Humans
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Mutation
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Neoplasm Proteins / genetics*
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Proto-Oncogene Proteins / genetics
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Tumor Suppressor Protein p53 / genetics
Substances
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BRCA1 Protein
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BRCA2 Protein
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CDKN1A protein, human
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Cyclin-Dependent Kinase Inhibitor p16
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Cyclin-Dependent Kinase Inhibitor p21
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Cyclins
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Neoplasm Proteins
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Proto-Oncogene Proteins
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Tumor Suppressor Protein p53