Trisomy 4 as the sole cytogenetic abnormality in a Waldenström macroglobulinemia

Cancer Genet Cytogenet. 2002 Mar;133(2):172-3. doi: 10.1016/s0165-4608(01)00577-5.

Abstract

We report a case of Waldenström macroglobulinemia with trisomy 4 as the sole cytogenetic abnormality. Trisomy 4 has been reported previously in Waldenström macroglobulinemia, but only in conjunction with multiple chromosomal aberrations. Trisomy 4 has been reported in other hematologic malignancies including acute myeloid and lymphoid leukemias.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antigens, CD / metabolism
  • Blood Cell Count
  • Bone Marrow / pathology
  • Chromosome Aberrations
  • Chromosomes, Human, Pair 4 / genetics*
  • Flow Cytometry
  • Humans
  • Male
  • Trisomy / genetics*
  • Waldenstrom Macroglobulinemia / genetics*
  • Waldenstrom Macroglobulinemia / pathology

Substances

  • Antigens, CD