A signal process method for DNA segments separation in micro-channel electrophoresis

Biosens Bioelectron. 2002 Jun;17(6-7):619-23. doi: 10.1016/s0956-5663(02)00024-6.

Abstract

This paper presents a signal process method for DNA segments separation in micro-channel electrophoresis. It is developed and optimized by using a laser induced fluorescence (LIF) based detection system. In this detection system, signal is sampled and processed through a novel signal process module. The results show that this signal process method provides good signal-to-noise ratios and lower limit of detection (LOD).

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / genetics
  • DNA / isolation & purification*
  • Electrophoresis, Capillary / instrumentation*
  • Electrophoresis, Capillary / methods*
  • Fourier Analysis
  • Lasers
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted / instrumentation*
  • Spectrometry, Fluorescence / instrumentation*
  • Spectrometry, Fluorescence / methods
  • Stochastic Processes
  • Time Factors

Substances

  • DNA