Multiple plasma cell granuloma of the central nervous system: a unique case with brain and spinal cord involvement. Case report and review of literature

Spinal Cord. 2002 Apr;40(4):203-6. doi: 10.1038/sj.sc.3101271.

Abstract

Study design: Single subject (male, 34 years-of-age) case report.

Objectives: To describe a unique case of plasma cell granuloma (PCG) with simultaneous brain and spinal cord involvement.

Setting: Private hospital, capital city, Turkey.

Methods: The patient presented with headache and paraplega. T2 weighted MR images showed multiple hyperintense cerebral, cerebellar, brainstem and spinal cord lesions that enhanced homogeneously with contrast medium. The patient was operated on, and the two intramedullary spinal cord lesions at T11 and T12 were totally excised.

Results: After 3 months of an intense physiotherapy programme the patient was able to walk with help.

Conclusion: We report for the first time, the occurrence of multiple, simultaneous brain and intramedullary spinal cord plasma cell granulomas.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Diseases / diagnosis*
  • Brain Diseases / pathology
  • Brain Diseases / surgery
  • Granuloma, Plasma Cell / diagnosis*
  • Granuloma, Plasma Cell / pathology
  • Granuloma, Plasma Cell / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Spinal Cord Diseases / diagnosis*
  • Spinal Cord Diseases / pathology
  • Spinal Cord Diseases / surgery
  • Thoracic Vertebrae / pathology
  • Thoracic Vertebrae / surgery