Application of synchrotron X-ray imaging to phase objects in orthopedics

J Synchrotron Radiat. 2002 May 1;9(Pt 3):143-7. doi: 10.1107/s0909049502004624. Epub 2002 Apr 25.

Abstract

Novel imaging of the fine structures of the ribs of a pig and a specimen of human osteosarcoma utilizing the spatial coherence of X-rays was successfully performed with an incident X-ray energy of 30 keV at SPring-8, Japan. The image contrast appearing at the periphery of trabecular bone, small calcifications and small fractures is caused by the phase shift of the X-rays at the boundary of these objects that have different X-ray refractive indices. The image is recorded on mammography film without an intensifying screen. Comparison of the image contrast using different sample-to-film distances, Z, such as Z = 5 m and Z approximately 0 m, showed that the former images were always more informative, i.e. better in resolution and/or image contrast when imaging trabecular bone, bone marrow and small fractures in compact bone, and for imaging cartilage. Radiography using synchrotron X-rays for phase objects should be a powerful tool for diagnosis in orthopedics, especially for bone disease.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bone Neoplasms / diagnosis
  • Bone and Bones / diagnostic imaging
  • Equipment Design
  • Humans
  • Japan
  • Models, Theoretical
  • Orthopedics*
  • Osteosarcoma / diagnosis
  • Radiographic Image Enhancement / methods*
  • Swine
  • Synchrotrons*