Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?

Circulation. 2002 Apr 30;105(17):2107-11. doi: 10.1161/01.cir.0000014762.06201.06.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antioxidants / administration & dosage
  • Antioxidants / therapeutic use*
  • Arteriosclerosis / drug therapy*
  • Arteriosclerosis / etiology
  • Arteriosclerosis / metabolism
  • Biomarkers / analysis
  • Clinical Trials as Topic
  • Disease Models, Animal
  • Humans
  • Lipoproteins, LDL / metabolism
  • Models, Cardiovascular*
  • Oxidation-Reduction
  • Oxidative Stress
  • Species Specificity

Substances

  • Antioxidants
  • Biomarkers
  • Lipoproteins, LDL
  • oxidized low density lipoprotein