Abstract
Diffusion-tensor MR imaging is a promising tool to evaluate white-matter integrity by quantitative and graphic maps including neural fiber tractogram. Current challenges afoot are to obtain higher quality diffusion-weighted MR images (high SNR, isotropic voxel, and high spatial resolution), to create a robust mathematical framework to process the data, to construct a user-friendly computer-based algorithm, to reveal determinants of diffusion process, and to establish analytical methodology.
MeSH terms
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Adrenoleukodystrophy / diagnosis
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Adrenoleukodystrophy / pathology
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Animals
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Blood-Brain Barrier / physiology*
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Brain Diseases / diagnosis*
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Brain Diseases / pathology
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Cerebral Palsy / diagnosis
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Cerebral Palsy / pathology
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Diffusion
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Holoprosencephaly / diagnosis
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Holoprosencephaly / pathology
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Humans
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Image Enhancement / methods*
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Image Processing, Computer-Assisted / methods*
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Imaging, Three-Dimensional*
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Magnetic Resonance Imaging / methods*
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Mice
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Nerve Fibers / pathology*
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Neural Pathways / pathology