Investigation of haematological and biochemical side effects of tilmicosin in healthy New Zealand rabbits

J Vet Med B Infect Dis Vet Public Health. 2002 Mar;49(2):68-70. doi: 10.1046/j.1439-0450.2002.00502.x.

Abstract

In this study, the effects of tilmicosin on some haematological and biochemical variables were investigated. Ten male New Zealand rabbits were used as material. The tilmicosin was injected (25 mg/kg body weight, subcutaneously as a single injection), and the rabbits were monitored for 4 days. No negative effects of tilmicosin on haematological and biochemical variables were observed, but it did cause a temporary decrease in red and white blood cell counts.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / pharmacology*
  • Blood Cell Count / veterinary
  • Blood Chemical Analysis / veterinary
  • Hemodynamics / drug effects*
  • Injections, Subcutaneous / veterinary
  • Liver / drug effects
  • Liver / metabolism
  • Liver Function Tests / veterinary
  • Macrolides*
  • Rabbits / metabolism*
  • Tylosin / administration & dosage
  • Tylosin / analogs & derivatives*
  • Tylosin / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Macrolides
  • tilmicosin
  • Tylosin