Mutations in the pancreatic secretory trypsin inhibitor gene (PSTI/SPINK1) rather than the cationic trypsinogen gene (PRSS1) are significantly associated with tropical calcific pancreatitis

J Med Genet. 2002 May;39(5):347-51. doi: 10.1136/jmg.39.5.347.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Adult
  • Base Sequence
  • Calcinosis / complications
  • Calcinosis / diagnosis
  • Calcinosis / genetics*
  • Chronic Disease
  • DNA Mutational Analysis
  • Diabetes Complications
  • Female
  • Genetic Predisposition to Disease*
  • Humans
  • Male
  • Middle Aged
  • Mutation
  • Pancreatitis / complications
  • Pancreatitis / diagnosis
  • Pancreatitis / genetics*
  • Pancreatitis / pathology
  • Phenotype
  • Trypsin Inhibitor, Kazal Pancreatic / genetics*
  • Trypsin*
  • Trypsinogen / genetics*

Substances

  • Trypsin Inhibitor, Kazal Pancreatic
  • Trypsinogen
  • PRSS1 protein, human
  • Trypsin