Abstract
Two new steroidal saponins were isolated from the Chinese folk medicine called Gualou-xiebai-baijiu-tang. The structures were determined to be spirost 25(27)-ene-2beta,3beta-diol-3-O-beta-D-glucopyranosyl(1-->2)-beta-D-galactopyranoside and 26-O-beta-D-glucopyranosyl-22alpha-hydroxy-5beta-furost-25(27)-ene-1beta,3beta,6beta,26-tetraol-3-O-beta-D-galactopyranoside, respectively, based on chemical evidences and spectral analysis.
MeSH terms
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Animals
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Drugs, Chinese Herbal / chemistry
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Hydrolysis
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In Vitro Techniques
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Magnetic Resonance Spectroscopy
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Plants, Medicinal / chemistry*
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Platelet Aggregation / drug effects
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Rabbits
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Saponins / chemistry*
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Saponins / isolation & purification
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Spectrometry, Mass, Fast Atom Bombardment
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Spectrophotometry, Infrared
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Spiro Compounds / chemistry*
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Spiro Compounds / isolation & purification
Substances
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25(27)-ene-2,3-diol-3-O-glucopyranosyl(1-2)-galactopyranoside
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26-O-glucopyranosyl-22alpha-hydroxy-5-furost-25(27)-ene-1,3,6,26-tetraol-3-O-galactopyranoside
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Drugs, Chinese Herbal
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Saponins
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Spiro Compounds