Abstract
Acetylation of proteins, either on various amino-terminal residues or on the epsilon-amino group of lysine residues, is catalyzed by a wide range of acetyltransferases. Amino-terminal acetylation occurs on the bulk of eukaryotic proteins and on regulatory peptides, whereas lysine acetylation occurs at different positions on a variety of proteins, including histones, transcription factors, nuclear import factors, and alpha-tubulin.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Acetylation
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Acetyltransferases / metabolism
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Animals
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Bacterial Proteins / metabolism
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Eukaryotic Cells / chemistry
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Eukaryotic Cells / metabolism
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Genetic Variation*
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Humans
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Lysine / metabolism
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Peptides / metabolism
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Protein Processing, Post-Translational / genetics*
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Proteins / metabolism
Substances
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Bacterial Proteins
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Peptides
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Proteins
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Acetyltransferases
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Lysine