Abstract
Host larvae of Drosophila melanogaster injected with the eicosanoid biosynthesis inhibitor, dexamethasone, prior to parasitization by the wasp Leptopilina boulardi, exhibited significantly reduced rates of melanotic encapsulation in comparison with control and saline-injected larvae. The results of this investigation suggest that prostaglandins and other eicosanoids are involved as cell-signaling molecules in the hemocytic encapsulation reaction of D. melanogaster larvae.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Anti-Inflammatory Agents / immunology
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Anti-Inflammatory Agents / pharmacology*
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Dexamethasone / immunology
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Dexamethasone / pharmacology*
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Drosophila melanogaster / drug effects
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Drosophila melanogaster / immunology*
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Drosophila melanogaster / parasitology
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Wasps / immunology*
Substances
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Anti-Inflammatory Agents
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Dexamethasone