Abstract
The interchromosome domain (ICD) model proposes that genes are selectively positioned at the surfaces of chromosome territories to facilitate their regulation. A paper in the May 13 issue of the Journal of Cell Biology provides evidence that supports a reinterpretation of this model.
MeSH terms
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Cell Nucleus / genetics
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Centromere / chemistry
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Chromosome Mapping
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Chromosome Painting
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Chromosomes* / genetics
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Euchromatin / genetics
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Gene Expression Regulation*
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Heterochromatin / chemistry
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Interphase
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Models, Biological
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Transcription, Genetic / genetics*
Substances
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Euchromatin
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Heterochromatin